Hypokalaemia, Metabolic Alkalosis, and Hypernatraemia due to "Massive" Sodium Penicillin Therapy

A rare cause of hypokalaemia and metabolic alkalosis

A 72-year-old man with a medical history of diabetes mellitus Type II, paroxysmal atrial fibrillation and heart failure was hospitalized after a syncope. Pitting oedema in both legs were the only abnormal finding on physical examination, in particular the patient had no cushinoid features. The blood pressure was slightly elevated at 160/90 mmHg. Regular medications consisted of furosemid 100 mg...

Severe metabolic alkalosis due to choledochoduodenal fistula.

Hyperventilation of pregnancy presenting with flaccid quadriparesis due to hypokalaemia secondary to respiratory alkalosis.

Hyperventilation in pregnancy is a cause of chronic respiratory alkalosis. Alkalosis either metabolic or respiratory may cause intracellular shift of potassium ions that may lead to hypokalaemia. However, the resultant hypokalaemia in respiratory alkalosis is usually mild and does not cause much clinical features. A five-months-pregnant female of the age 25 years presented with sudden onset fla...

Effect of amiloride on metabolic alkalosis and hypokalaemia after cardiopulmonary bypass surgery.

This study was undertaken to investigate the effects of the potassium-retaining diuretic, amiloride, on the potassium balance and on the alkalosis which occurs in patients after open-heart surgery. Patients who had had valve replacement operations were divided randomly into two groups, one of which received Io mg amiloride daily in the postoperative period. Patients who were given amiloride nee...

Approach to metabolic alkalosis.

Metabolic alkalosis is a common disorder, accounting for half of all acid-base disturbances in hospitalized patients. It is the result of an increase in bicarbonate production, a decrease in bicarbonate excretion, or a loss of hydrogen ions. Most causes of metabolic alkalosis can be divided into 4 categories: chloride depletion alkalosis, mineralocorticoid excess syndromes, apparent mineralocor...